Amlodipine-induced gingival overgrowth in a child after liver transplant
نویسندگان
چکیده
Drug-induced gingival overgrowth (GO) has been associated with phenytoin, cyclosporine, and calcium channel blocker therapies. This study reports the case of an 11-year-old girl who was referred for evaluation of GO, which had occurred over the last 6 months. Her medical history included a liver transplant due to biliary atresia 3 years ago, immunosuppressive therapy, and hypertension, which is why she was started on a daily intake of amlodipine. The intraoral examination showed generalized GO, and the treatment consisted of a gingivectomy. Subsequently, amlodipine was replaced with captopril and oral hygiene instructions. There was no recurrence of GO after 28 months of follow-up. Although GO may be related to the chronic use of amlodipine, such an association is uncommon in pediatrics, and the treatment consists of the replacement of medication combined with a surgical approach and plaque control.
منابع مشابه
بررسی تأثیر آزیترومایسین در درمان افزایش حجم لثه ناشی از مصرف سیکلوسپورین در بیماران پیوند کلیه
Statement of Problem: Gingival overgrowth is a side effect commonly induced by Cyclosporin treatment. The effects of Azithromycin, a macrolidic antibiotic, has been focused on gingival enlargement treatment induced by cyclosporine in numerous articles. Purpose: The goal of the present study was to survey the effects of systemic Azithromycin in the treatment of gingival overgrowth induced by cyc...
متن کاملAmlodipine- induced gingival overgrowth: a case report.
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295 ABSTRACT: Gingival overgrowth (GO) is one of the most important clinical features of gingival pathology. Amlodipine is a comparatively new III generation calcium channels blocker, used for management of cardiovascular disorders. Although it is considered safe, it can also rarely induce GO. A case of severe amlodipine-induced GO, complicated by inflammatory changes due to plaque accumulation...
متن کاملAmlodipine induced gingival overgrowth: A case report
Introduction: Drug-induced gingival overgrowth (DIGO) remains a significant problem for the dental clinicians and the periodontologists. Patients medicated with certain drugs may be implicated in this unwanted side effect, which may interfere with esthetics, mastication or speech. Case Report: The case presented here is a 60-year-old female patient with drug induced gingival enlargement. Patien...
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2016